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Matrine powder Raw Materials CAS 519-02-8
Product Overview:
Matrine powder, also known as matrine, is an alkaloid extracted from the roots, stems and fruits of Matrine, a leguminous plant, by ethanol and other organic solvents. It belongs to lupine alkaloids, derivatives of quinolisidine. Matrine Raw Materials have the characteristics of specificity and natural, and can decompose quickly in nature, and the final products are carbon dioxide and water. Is a green, environmentally friendly insecticide. Matrine CAS 519-02-8 is an alkaloid made from dried roots, plants and fruits of Matrine, a leguminous plant, extracted by ethanol and other organic solvents. It is generally a total matrine base, and its main components are matrine, sophorine, sophorine oxide, sophoridine and other alkaloids, with matrine and oxymatrine having the highest content. Other sources are the root and the aboveground part of the root. Pure product appearance is white powder.
Matrine powder Raw Materials CAS 519-02-8 Attributes
MF:C15H24N2O
MW:248.36
EINECS:610-750-6
Specification:99% min Matrine powder
Sample:Matrine powder Avaliable
Appearance:white powder
Storage: Cool Dry Place
Brand: Ausreson
Shelf Life: 2 Years
Test Method: HPLC
Matrine powder Raw Materials CAS 519-02-8 Details
Uses and synthesis of Matrine powder
Matrine powder, also known as matrine, is an alkaloid extracted from the roots, stems and fruits of Matrine, a leguminous plant, by ethanol and other organic solvents. It belongs to lupine alkaloids, derivatives of quinolisidine. Matrine Raw Materials have the characteristics of specificity and natural, and can decompose quickly in nature, and the final products are carbon dioxide and water. Is a green, environmentally friendly insecticide. Matrine CAS 519-02-8 is an alkaloid made from dried roots, plants and fruits of Matrine, a leguminous plant, extracted by ethanol and other organic solvents. It is generally a total matrine base, and its main components are matrine, sophorine, sophorine oxide, sophoridine and other alkaloids, with matrine and oxymatrine having the highest content. Other sources are the root and the aboveground part of the root. Pure product appearance is white powder.
Applications/Functions of Matrine powder
Matrine powder antibacterial and anti-inflammatory drug for chronic cervicitis, dysentery, enteritis, etc.
Matrine CAS 519-02-8 diuretic effect, antipathogen effect
1. Anti-inflammatory and immunomodulatory effects
Inhibit NF-κB pathway, reduce pro-inflammatory factors such as IL-6 and TNF-α (International Immunopharmacology, 2021)
Regulate Th1/Th2 immune balance, may improve allergic diseases
2. Antiviral activity
Shows inhibitory effects on hepatitis B virus (HBV) and influenza virus (Virology Journal, 2020)
Mechanism: Blocking viral replication cycle
3. Anti-fibrotic effect
Inhibit liver/pulmonary fibrosis through TGF-β/Smad pathway (Journal of Ethnopharmacology, 2022)
4. Other research areas
Anti-tumor: Induces tumor cell apoptosis (in vitro study)
Neuroprotection: Potential application in Alzheimer's disease
Cardiovascular protection: Improves myocardial ischemia
Clinical Application of Matrine.
| Application direction | Evidence level | Research progress |
| Chronic hepatitis adjuvant treatment | Phase II clinical trial | China has approved related drugs |
| Eczema/dermatitis | Multicenter RCT | Significantly improves itching symptoms |
| Anti-liver fibrosis | Animal model | The mechanism is clear, more people need to try |
| Tumor adjuvant therapy | Preclinical | Combination chemotherapy research in progress |
Physicochemical Property of Matrine powder
The main components of matrine are matrine, oxymatrine, sophorine, oxysophorine, sophoridine, etc. The content of matrine and oxymatrine is the highest. Matrine Raw Materials are soluble in water, benzene, chloroform, ether and carbon dioxide, and insoluble in petroleum ethers. Derived from the dried root of the leguminous Sophora flavescens Ait.
FAQ.
Q1: Which one has better anti-inflammatory effect, matrine or purslane extract?
A: Different mechanisms of action. Matrine is more suitable for systemic inflammation, while purslane extract is milder for skin inflammation.
Q2: How long does it take to take effect?
A: Immunomodulation takes 4-8 weeks, and improvement of skin diseases may take 2-4 weeks.
Q3: Can it be used in combination with conventional drugs?
A: It needs to be taken at intervals of 2 hours, especially immunosuppressants.
Q4: Is there drug resistance?
A: It has not been observed yet, but it is recommended to use it continuously for no more than 6 months per year.
