Supplement Menadione powder Raw Materials CAS 58-27-5

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Product details

Uses and synthesis of Menadione powder

Menadione powder is white or quasi-white crystalline powder, caked after hygroscopic. It is easily soluble in water and hot ethanol, difficult to dissolve in ice ethanol, insoluble in benzene and aqueous solution PH4.7-7. Stable at room temperature, easy to decompose when exposed to light. Menadione is a procoagulant, which can be used to treat some bleeding disorders caused by vitamin K deficiency. Vitamin K3, also known as Menadione, can promote the formation of prothrombin, and also has a diuretic effect, which can lower blood pressure. Vitamin K3 is sometimes used as a coloring agent or food additive. Menadione powder can promote prothrombin synthesis and plasma coagulation factor synthesis in the liver of livestock and poultry.

Vitamin K deficiency: for coagulation disorders such as those caused by neonatal bleeding, prolonged diarrhea, or obstructive jaundice.
Hypoprothrombinemia: for coagulation abnormalities caused by overdose of oral anticoagulants (e.g. warfarin) or liver disease.
Trauma or postoperative bleeding: adjunctive treatment for substantial organ bleeding and postoperative hemostasis

Functions of Menadione  powder

• Biochemical research, clinical drug belongs to fat-soluble vitamin, clinical as a hemostatic.
• Menadione powder is mainly used as a feed fortification for poultry.
• Feed additive raw material, mainly can promote the synthesis of prothrombin in the liver of livestock and poultry, and promote the synthesis of plasma coagulation factor in the liver, as a hemostatic agent.
• Menadione can promote the synthesis of prothrombin in the liver of livestock and poultry, and promote the synthesis of plasma coagulation factor in the liver.

Applications of Menadione  powder

I. Medical Field

Coagulation regulation
Used in the treatment of vitamin K deficiency (e.g., coagulation disorders caused by neonatal bleeding, prolonged diarrhea or jaundice) and hypoprothrombinemia (caused by overdose of oral anticoagulants or liver disease).
Injections are used for acute hemorrhage (e.g., substantial organ injury, post-operative hemostasis) and for the relief of poisoning by the rodenticide Sodium Dichlorvos.

Bone and Skin Health
Promote bone growth and maintenance of bone density, prevent osteoporosis.
Improve skin erythema and ecchymosis, assist skin repair and whitening.

Metabolic Regulation
Improve insulin sensitivity and assist in controlling blood sugar level.

II. Food Industry

As a food additive, used in dairy products, meat products, baked goods, beverages, etc., to enhance nutritional stability and extend shelf life.

Animal breeding
Add to animal feed to promote prothrombin synthesis, maintain normal blood clotting function, support animal growth and health.

Other Uses
Derivatives (e.g. methyl naphthoquinone acetate) are used in the development of pharmaceutical preparations with higher stability.
 

How to use Menadione correctly?

Adults.
Oral: regular dose of 2-4mg per dose, 3 times daily (maximum single daily dose ≤15mg).
Intramuscular: 2-4mg each time, twice daily, for acute bleeding or when oral administration is not possible.
Children
Oral: 3-7 μg/kg based on body weight, 3 times daily.
Neonates
Prevention of hemorrhage: intramuscular injection to pregnant women 1 week before delivery, 2-4 mg daily.
Treatment of hemorrhage: adjust dose as needed after birth, preferably intramuscularly

Production methodprocess of Menadione powder

Menadione powder was prepared from o-methylnaphthoquinone by oxidation and addition.

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