Amoxicillin powder Raw Materials CAS 26787-78-0

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Uses and synthesis of Amoxicillin powder

​​Amoxicillin powder, also known as Amoxicillin or Ammoxicillin, is one of the most commonly used penicillin-based broad-spectrum beta-lactam antibiotics, a white powder with a half-life of about 61.3 minutes. It is stable under acidic conditions, with a gastrointestinal absorption rate of 90%, and has strong bactericidal effect and the ability to penetrate cell membranes. Amoxicillin is also one of the semi-synthetic penicillin that is widely used in clinical practice. Amoxicillin is mainly used to treat inflammation caused by upper and lower respiratory tract infections, such as otitis media, sinusitis. Acute urethritis and other more serious inflammation. And the effect of amoxicillin is very wide, the effect is very fast, after swallowing can be well absorbed by the stomach and intestines, is a better antibiotic drug.

​​​Applications/Functions of Amoxicillin powder

1. ​​Amoxicillin powder can be used as a broad spectrum semi-synthetic penicillin. Clinically used for the treatment of tonsillitis, laryngitis, pneumonia, chronic bronchitis, urinary system infection, skin soft tissue infection, suppurative pleurisy, liver and bile system infection, septicemia, typhoid, dysentery and so on.
2. ​Amoxicillin is an antimicrobial spectrum drug, and its action and application are similar to clopicillin, with the advantage that the serum protein binding rate is low and the blood concentration is more than two times higher than ampicillin.

​​Physicochemical Property of Amoxicillin powder

​​​Amoxicillin white crystalline powder. The melting point of the trihydrate is 195℃ (decomposition), solubility (mg/ml), water 4.0, methanol 7.5, and anhydrous ethanol 3.4. The pH of the aqueous solution is about 4.7. It tastes slightly bitter.

FAQ.

Q1: Is amoxicillin effective against viral infections?
A: No. Amoxicillin is only effective against bacterial infections and is ineffective against viral infections such as the common cold and influenza.

Q2: What should I do if I miss a dose?
A: If it is close to the next scheduled dose, skip the missed dose; otherwise, take the missed dose immediately. Do not double the dose.

Q3: Can amoxicillin lead to antibiotic resistance?
A: Improper use (such as not completing the full course of treatment or unnecessary use) may lead to the development of bacterial resistance.

Q4: Does alcohol affect the effectiveness of amoxicillin?
A: While it does not directly reduce the drug's efficacy, it may increase gastrointestinal side effects and affect the immune system.

Q5: Does amoxicillin need to be refrigerated?
A: Tablets/capsules do not require refrigeration, but liquid formulations typically need to be refrigerated after opening.

Amoxicillin may interact with the following drugs:

Probenecid: May increase the blood concentration of amoxicillin.

Oral contraceptives: May reduce contraceptive effectiveness.

Anticoagulants: May enhance anticoagulant effects.

Allopurinol: Increases the risk of rash.

Other antibiotics: May produce antagonistic effects.

​​​Production methodprocess of Amoxicillin powder

​Amoxicillin powder was prepared by condensation of 6-APA with N- (3-ethoxycarbonyl 1-methylvinyl-p-hydroxyphenylglycine sodium salt.

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