Gallic acid monohydrate Amazon powder Raw CAS 5995-86-8

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Product details

Uses and synthesis of Gallic acid monohydrate powder

Gallic acid monohydrate powder is a natural polyhydroxyl phenolic compound. Gallic acid monohydrate is white to beige solid at room temperature and pressure. It has strong acidity. It can inhibit the free radical scavenging of cyclooxygenase-2 (COX-2). Gallic acid monohydrate has a wide range of uses in pharmaceutical, food and light industry. It is also used as an analytical reagent, in the manufacture of ink and photography.

Functions of Gallic acid monohydrate powder.

Application of Gallic Acid Monohydrate.

1. As Food and beverage ingredients. 2. As Healthy Products ingredients. 3. As Nutrition Supplements ingredients. 4. As Industry ingredients.

Antioxidants
Gallic acid is often used in pharmaceutical preparations as an antioxidant for oils and oil-containing preparations. It is also used as an antioxidant in the food and cosmetic industries for the manufacture of food and cosmetics; it is also a raw material for the manufacture of alkyl gallic acid. 

Antibacterial, antiviral
It can inhibit Staphylococcus aureus, Neisseria, Pseudomonas aeruginosa, dysentery bacillus, typhoid fever bacillus, paratyphoid fever bacillus, etc. The concentration of its bacteriostatic agent is 5mg/ml. In vitro, it has bacteriostatic effect on 17 kinds of fungi in 3% concentration, and it has some inhibitory effect on influenza virus.
 
Anti-tumor
It has strong inhibitory effect on lung adenoma caused by morpholine plus sodium nitrite in mice.

Primary Applications

Physicochemical Property of Gallic acid monohydrate powder.

White or light yellow acicular crystals, or prismatic crystals. It has a silk luster and a slightly sour taste. Soluble in ethanol, acetone, ethylene glycol, slightly soluble in water, ether.

Gallic acid contains both three active phenolic hydroxyl groups and one carboxyl group in the molecule, and can be synthesized into a variety of ethers, chlorides, and esters.
First, etherification followed by esterification, i.e., etherification at the phenolic hydroxyl group to produce 3,4,5-trihydrocarbonyloxybenzoic acid, followed by esterification at the carboxyl group to synthesize alkyl esters of 3,4,5-trihydrocarbonyloxybenzoic acid;

Second, esterification followed by etherification, i.e., esterification in the carboxyl part first to produce 3,4,5-trihydroxybenzoic acid ester, and then etherification in the phenolic hydroxyl part can also be synthesized ;
Thirdly, simultaneous etherification and esterification, i.e., etherification of the phenolic hydroxyl portion and esterification of the carboxyl portion are carried out at the same time, can lead to the direct synthesis of the compound.

If 2 is reacted with chlorochloridyl chloride to form 3,4,5-trihydrocarbonyloxybenzoyl chloride, 3 can also be synthesized by the phenolysis reaction of chloride with phenolics to form aryl esters of 3,4,5-trihydrocarbonyloxybenzoic acid, which are different from 

Preparation method of Gallic acid monohydrate powder

Acid Hydrolysis

Acid hydrolysis is mainly divided into one-step method and two-step method. The main process flow of two-step gallic acid preparation: raw materials, hot water extraction, filtration and removal of filter residue, concentration of aqueous tannin solution to about 20%, acid hydrolysis, cooling and crystallization, centrifugation of crude product, dissolution of crude product and decoloration with charcoal, filtration and cooling and crystallization, centrifugation and drying, and finished product of gallic acid. The process of preparing gallic acid by one-step method is to omit the step of tannin extraction and hydrolyze it with acid directly, which eliminates the process of crushing, extraction and concentration.

However, the sulfuric acid used in the acid hydrolysis method is a strong acid, and there are different degrees of corrosion on the equipment. Although the reaction filter and freezing kettle are made of stainless steel, but due to the high reaction temperature, acid concentration is larger, corrosion is more obvious, directly affecting the service life of the equipment!

FAQ.

Q: Is gallic acid monohydrate safe during pregnancy?
A: No clinical data available - consult healthcare provider before use.

Q: What's the difference between anhydrous and monohydrate forms?
A: Monohydrate contains 8-10% water, making it more stable but slightly less potent by weight.

Use the product safely.

The U.S. Food and Drug Administration (FDA) is an important agency of the U.S. federal government responsible for regulating food, drugs, medical devices, cosmetics, biological products, and tobacco products to ensure their safety, effectiveness, and quality. Food and dietary supplements can support your overall health, please use them wisely.

Company advantages.

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We have our own R&D team and workshop, and can provide customized services according to your needs. We have strict quality control on the production side, set up multiple inspection points in the production process, find and correct problems in time, and conduct comprehensive inspections on finished products to ensure that the products meet quality requirements.

We have 20 years of industry experience and always adhere to quality first to provide customers with the most reliable products and services.
 

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