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O-304 AMPK activator is an orally active pan-activator of AMPK activated protein kinase (AMPK). O-304 (O-304X) has great potential as a new drug for the treatment of type 2 diabetes (T2D) and related cardiovascular complications.
Does O-304 work for weight loss?
1.AMPK Activation → Metabolic Boost
Mimics exercise-induced fat oxidation (increases cellular energy demand)
Preclinical studies show 27% reduction in visceral fat in obese mice (vs. 12% with metformin)
2.Mitochondrial Uncoupling
Generates heat instead of ATP ("wastes" calories)
Similar mechanism to cold exposure/brown fat activation
3.Appetite Suppression (Indirect)
AMPK modulates leptin sensitivity (animal data only)
Comparative Analysis
Compound | Target | Bioavailability | Side Effect Profile |
---|---|---|---|
O-304 | AMPK β1 | 92% oral (mouse) | Mild thermogenesis |
Metformin | AMPK indirect | 50-60% | GI distress |
Berberine | Systemic AMPK | <5% | Drug interactions |
SR9009 | REV-ERBα | Poor oral | Sleep disruption |
Use the product safely.
The U.S. Food and Drug Administration (FDA) is an important agency of the U.S. federal government responsible for regulating food, drugs, medical devices, cosmetics, biological products, and tobacco products to ensure their safety, effectiveness, and quality. Food and dietary supplements can support your overall health, please use them wisely.
Company advantages.
We have 20 years of industry experience and always adhere to quality first to provide customers with the most reliable products and services.
We have our own R&D team and workshop, and can provide customized services according to your needs. We have strict quality control on the production side, set up multiple inspection points in the production process, find and correct problems in time, and conduct comprehensive inspections on finished products to ensure that the products meet quality requirements.
In addition to plant extracts, vitamins, mineral supplements and food additives, our main products include capsules, soft capsules, solid beverages, soft candies, drops, gels, tablets and effervescent tablets. We can customize labels and product formulas according to your needs until you are satisfied.
We are customer-centric, provide 7*24 hours all-weather service, and respond quickly to customer needs.
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