Ausreson 4-acetyl-2-methylbenzoic acid powder Raw Materials CAS 55860-35-0

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Uses and synthesis of 4-acetyl-2-methylbenzoic acid powder

As a white or light white solid, 4-acetyl-2-methylbenzoic acid powder can be used as an organic synthesis intermediate and pharmaceutical intermediate, mainly for laboratory research and chemical production processes. 4-acetyl-2-methylbenzoic acid is one of the intermediates of halothane amides, which can be used to improve soil.

Functions of 4-acetyl-2-methylbenzoic acid powder

4-acetyl-2-methylbenzoic acid powder can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Applications of 4-acetyl-2-methylbenzoic acid powder

Pesticide intermediates ‌
As the core synthetic raw material of isoxazoline insecticides such as Fluralaner and Isocycloseram, the acetyl and carboxylic acid groups in its molecular structure play a key role in the activity of pesticides.

‌Pharmaceutical intermediates ‌
Used for structural modification of benzoic acid bioactive molecules, such as the synthesis of amide derivatives, and potential application in drug research and development.

‌Organic synthesis and scientific research ‌
As a bifunctional aromatic compound, it can be used for esterification, condensation and other reactions, and is extended to fine chemical fields such as dyes and liquid crystal materials.

Product Menthod of 4-acetyl-2-methylbenzoic acid powder

‌Friedel-Crafts acylation-oxidation method‌
Using m-fluorotoluene and acetyl chloride as starting materials, Friedel-Crafts acylation reaction occurs under the catalysis of anhydrous aluminum chloride, and then hydrolyzed by sodium hypochlorite haloform reaction, the isomers are separated to obtain the target product.

‌Direct oxidation method‌
Using 3,4-dimethylacetophenone as raw material, it is directly oxidized and synthesized under the action of aqueous hydrogen peroxide solution and catalyst, and the reaction initiation conditions in polar organic solvents need to be controlled.

‌Precursor acylation method‌
The precursor is generated by the reaction of 2-methylbenzoic acid with acetoacetate, and then treated step by step with thionyl chloride and copper chloride, and finally hydrolyzed and purified to obtain the product.

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