Chlorphenamine maleate powder Raw Materials CAS 113-92-8

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Uses and synthesis of Chlorphenamine maleate powder

​​Chlorphenamine maleate powder is a white crystalline powder. Odorless, bitter taste. Soluble in water, ethanol or chloroform, slightly soluble in ether. Chlorphenamine maleate is used for allergic rhinitis, colds and sinusitis and allergic skin disorders such as urticaria, allergic drug rash or eczema, angioneurotic edema, and itchy skin caused by insect bites. Chlorphenamine maleate not only has a strong competitive blocking effect on histamine H1 receptor on target cells of allergic reaction, but also has an anti-allergy effect through antagonism of H1 receptor. Therefore, chlorphenamine maleate can cause symptoms such as dry mouth, constipation, thickening of sputum, dry nasal mucosa, etc. In addition, Chlorphenamine maleate powder also has a certain inhibitory effect on the central system, so adverse reactions to drowsiness may occur after taking the drug.

​​​Applications/Functions of Chlorphenamine maleate powder

• ​​Chlorphenamine maleate powder has a higher antihistamine effect than diphenhydramine and promethazine. The dosage is small and the side effects are mild. It is used for urticaria, vasodilator rhinitis, cold, asthma, rhinitis, contact dermatitis, and allergy caused by drugs and food, insect bites and motion sickness.
• ​Antihistamines. Similar to Cloromitone, bromphenyramide is also an antihistamine. Bromphenyramide is also produced in a similar way to cloromitone, except that the starting material is replaced by a bromobenzene compound.
• ​Chlorphenamine maleate is used as an anti-allergy drug

​​​Physicochemical Property of Chlorphenamine maleate powder

​​​The chemical properties? White crystalline powder. Melting point 131-135℃. Soluble in water, ethanol, chloroform, slightly soluble in ether, odorless, bitter taste.

​​​Production methodprocess of Chlorphenamine maleate powder

​Chlorphenamine maleate powder is prepared by salting chlordromitone with maleic acid.

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