Artemisinin powder Raw Materials CAS 63968-64-9

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Uses and synthesis of Artemisinin powder

​​Artemisinin powder is a sesquiterpene lactone drug with peroxy groups extracted from the stems and leaves of Artemisia flannellae. The main effect of Artemisinin on the ultrastructure of Plasmodium falciparum is the change of the structure of plasmodium membrane. Artemisinin first acts on food vesicles, surface membranes, mitochondria, endoplasmic reticulum, and also has a certain effect on chromatin. Artemisinin is an effective drug for the treatment of malaria. It is a sesquiterpene lactone drug with peroxy groups extracted from Artemisinin, a traditional Chinese medicine. Artemisinin powder has the characteristics of high efficiency, quick effect, clearing heat and summer heat, eliminating asthenic heat, killing protozoa, and low toxicity. At present, artemisinin-based combination therapy (ACT) used to treat malaria around the world has achieved more than 90% efficacy, and has been widely used in the treatment of malaria in countries around the world.

​​​Applications/Functions of Artemisinin powder

• ​Artemisinin powder is used as an antimalarial drug, and artemisinin and its derivatives have been shown to be effective against malaria and falciparum malaria in clinical applications, especially Artemtherin, which is more potent than other artemisinin-based drugs in reducing plasmodium intracellular asexuals. Artemisinin has the advantages of high efficiency, rapid action, low toxicity and no cross resistance to chloroquine, which can be used not only for treatment, but also for emergency treatment.
• ​Artemisinin first acts on food vesicles, membranes, mitochondria, endoplasmic reticulum, and has certain effects on chromatin. It is suggested that artemisinin's action mode is mainly to interfere with the function of the membrane-mitochondria.

​​​Physicochemical Property of Artemisinin powder

​​​Colorless acicular crystal. Melting point 156-157℃. Soluble in chloroform, acetone, ethyl acetate and benzene, soluble in methanol, ethanol, insoluble in water.

​​​Production methodprocess of Artemisinin powder

​Artemisinin powder is extracted from the leaves of the Chinese herb Artemisia annua (Artemisia annua L, compositaceae).

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