Atorvastatin powder Raw Materials CAS 134523-00-5

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Uses and synthesis of Atorvastatin powder

Atorvastatin powder, a HMG-CoA reductase inhibitor in the form of calcium salts, was first registered in Germany and the United Kingdom in February 1997 and first approved for marketing in the United Kingdom in April 1997. The chemical called: - (R, R) [R] - 2 - (4 - fluorinated phenyl) - beta, beta 2 hydroxy - 5 - (1 - methyl ethyl) - 3-4 - [(aniline) carbonyl] phenyl - - 1 - hydrogen - pyrrole - 1 - heptanoic acid calcium, relative molecular mass of 1155.36. Atorvastatin is a commonly used statin in clinical practice. In addition to treating hypercholesterolemia, atorvastatin has a better preventive effect on hypertension, coronary heart disease and cerebrovascular disease

Applications/Functions of Atorvastatin powder

1. Lipid-lowering drugs. Atorvastatin powder inhibited the activity of HMG-CoA reductase, thereby reducing cholesterol synthesis.
2. Atorvastatin has multiple pharmacological effects, such as anti-atherosclerosis, anti-inflammation and lowering blood pressure
3. Atorvastatin powder is a commonly used statin drug in clinical practice. In addition to treating hypercholesterolemia, atorvastatin powder has a better preventive effect on hypertension, coronary heart disease and cerebrovascular diseases. In terms of cardiovascular diseases, atorvastatin can protect endothelial function, delay atherosclerosis, protect target organs and improve prognosis in patients with atherosclerosis

Physicochemical Property of Atorvastatin powder

Production methodprocess of Atorvastatin powder

Compound (I) is reduced with triethylboron and sodium borohydride in methanol, and the resulting product is hydrolyzed to obtain atorstatine sodium. Acidification can be obtained with Atorvastatin.

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